The following is an incomplete list of doping cases and recurring accusations of doping in professional cycling , where doping means ” use of physiological substances or abnormal method to obtain an artificial increase of performance “. Thus the list contains doping incidents, those who have tested positive for illegal performance-enhancing drugs , prohibited recreational drugs or have been suspended by a sports governing body for failure to submit to mandatory drug testing. It also contains and clarifies cases where subsequent evidence and explanation has shown the parties to be innocent of illegal practice. In , the Council of Europe gave a definition of doping. When necessity demands medical treatment with any substance which, because of its nature, dosage, or application is able to boost the athlete’s performance in competition in an artificial and unfair manner, this too is regarded as doping. In , a Welsh cyclist is popularly reputed to have died after drinking a blend of cocaine , caffeine and strychnine , supposedly in the Bordeaux—Paris race. This was included in the International Olympic Committee study on the Historical Evolution of Doping Phenomenon , and listed as the presumed first death due to doping during a competition. The report did allow that in this period it was common practice, and not illegal. Nitroglycerine was used to stimulate the heart after cardiac attacks and was credited with improving riders’ breathing. The American champion Major Taylor refused to continue a New York race, saying: “I cannot go on with safety, for there is a man chasing me around the ring with a knife in his hand.

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The city is the sixth-largest in France , with a population of , in Nantes and a metropolitan area of nearly , inhabitants. Nantes belongs historically and culturally to Brittany , a former duchy and province , and its omission from the modern administrative region of Brittany is controversial. Nantes was identified during classical antiquity as a port on the Loire. It was the seat of a bishopric at the end of the Roman era before it was conquered by the Bretons in Although Nantes was the primary residence of the 15th-century dukes of Brittany , Rennes became the provincial capital after the union of Brittany and France.

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Twenty-Seven Lower and Middle Paleolithic sites from Europe and the Middle East are reported in the literature to have yielded incised stones. At eleven of these sites incisions are present on flint cortexes. Even when it is possible to demonstrate that the engravings are ancient and human made, it is often difficult to distinguish incisions resulting from functional activities such as butchery or use as a cutting board, from those produced deliberately, and even more difficult to identify the scope of the latter.

In this paper we present results of the analysis of an engraved cortical flint flake found at Kiik-Koba, a key Mousterian site from Crimea, and create an interpretative framework to guide the interpretation of incised cortexes. The frame of inference that we propose allows for a reasoned evaluation of the actions playing a role in the marking process and aims at narrowing down the interpretation of the evidence.

The object comes from layer IV, the same layer in which a Neanderthal child burial was unearthed, which contains a para-Micoquian industry of Kiik-Koba type dated to between c. The microscopic analysis and 3D reconstruction of the grooves on the cortex of this small flint flake, demonstrate that the incisions represent a deliberate engraving made by a skilled craftsman, probably with two different points. The lines are nearly perfectly framed into the cortex, testifying of well controlled motions.

This is especially the case considering the small size of the object, which makes this a difficult task. The production of the engraving required excellent neuromotor and volitional control, which implies focused attention.

Proceedings of Réanimation 2018, the French Intensive Care Society International Congress

Twenty-Seven Lower and Middle Paleolithic sites from Europe and the Middle East are reported in the literature to have yielded incised stones. At eleven of these sites incisions are present on flint cortexes. Even when it is possible to demonstrate that the engravings are ancient and human made, it is often difficult to distinguish incisions resulting from functional activities such as butchery or use as a cutting board, from those produced deliberately, and even more difficult to identify the scope of the latter.

In this paper we present results of the analysis of an engraved cortical flint flake found at Kiik-Koba, a key Mousterian site from Crimea, and create an interpretative framework to guide the interpretation of incised cortexes. The frame of inference that we propose allows for a reasoned evaluation of the actions playing a role in the marking process and aims at narrowing down the interpretation of the evidence.

The object comes from layer IV, the same layer in which a Neanderthal child burial was unearthed, which contains a para-Micoquian industry of Kiik-Koba type dated to between c.

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